How Does Accutane (Isotretinoin) Work?

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    bruceparker
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    Accutane (Isotretinoin 40 mg) is a powerful medication used primarily to treat severe acne. It works by targeting several key factors in acne development. Firstly, isotretinoin significantly reduces the size and activity of sebaceous (oil) glands, leading to decreased oil production. This helps prevent clogged pores, which are a major cause of acne.

    Secondly, it promotes the renewal of skin cells and reduces the stickiness of cells within hair follicles, minimizing the likelihood of pore blockages. Additionally, isotretinoin has anti-inflammatory properties, which help reduce redness and swelling associated with acne lesions.

    Isotretinoin also decreases the presence of acne-causing bacteria (Propionibacterium acnes) on the skin. By tackling acne from multiple angles—oil production, cell turnover, inflammation, and bacterial presence—Accutane effectively clears severe, resistant acne that hasn’t responded to other treatments.

    However, its use requires close medical supervision due to potential side effects, including dry skin, liver issues, and severe birth defects if taken during pregnancy. Regular monitoring ensures safe and effective use of the medication.

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