Exosome cargo pre-loading is an emerging technique in the field of nanomedicine that involves the strategic incorporation of therapeutic agents, such as proteins, RNA, or small molecules, into exosomes before they are secreted by cells. This method leverages the natural ability of exosomes to facilitate cell-to-cell communication and deliver bioactive molecules across biological barriers. By optimizing exosome cargo pre-loading, researchers aim to enhance the delivery efficiency and targeting specificity of these nanocarriers in treating various diseases, including cancer and neurodegenerative disorders. The advancement of exosome cargo pre-loading techniques holds significant promise for developing next-generation therapies that are both effective and have reduced side effects.
